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These results, along with a preceding report demonstrating that a small-molecule ACKR3 agonist CCX771 displays anxiolytic-like actions in mice,2 help the strategy of targeting ACKR3 as a novel solution to modulate the opioid procedure, which could open up new therapeutic avenues for opioid-associated Ailments.A exploration research printed in Anest
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Here, we exhibit that conolidine, a organic analgesic alkaloid used in traditional Chinese medication, targets ACKR3, thus providing supplemental proof of the correlation involving ACKR3 and discomfort modulation and opening choice therapeutic avenues for that cure of Persistent pain.The rankings replicate our belief and should be an excellent star
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